base.html __init__.py asgi.py settings.py urls.py wsgi.py manage.py requirements.in cd myproject python -m manage runserver django CMS is nothing installations. For operating multiple websites using the same virtualenv you can use copies of manage.py, wsgi.py and different versions of settings and the URL configuration for each site. You can use the same DATABASES, ALLOWED_HOSTS etc., which may be site-specific or not. 1. Copy and edit wsgi.py and manage.py e. g. to wsgi_second_site.py and manage_second_site.py: Change the reference to the settings like