specifics for your wxPython release: if pix.alpha: bitmap = wx.Bitmap.FromBufferRGBA(pix.width, pix.height, pix.samples) else: bitmap = wx.Bitmap.FromBuffer(pix.width, pix.height, pix.samples) Tkinter interfacing with Pillow is almost trivial. Input Formats Output Formats Description BMP . Windows Bitmap JPEG JPEG Joint Photographic Experts Group JXR . JPEG Extended Range JPX/JP2 . JPEG 2000 GIF PNG Portable Network Graphics PNM PNM Portable Anymap PGM PGM Portable Graymap PBM PBM Portable Bitmap PPM PPM Portable Pixmap PAM PAM Portable Arbitrary Map . PSD Adobe Photoshop Document . PS Adobe

all the pixels as a Python bytes object. Here are two examples, find more here. wxPython: >>> bitmap = wx.BitmapFromBufferRGBA(pix.width, pix Tkinter: >>> # the following requires: "from PIL import